University Of Tehran Press Pollution 2383-451X 1 3 2015 07 01 Hematological responses of Goldfish (Carassiusauratus) to different acute concentrations of Silver Sulfate as a toxicant 247 256 53927 10.7508/pj.2015.03.001 EN Safoura Abarghoei Department of Fisheries, Gorgan University of Agricultural Sciences and Natural Resources, Goran, Iran Seyed Aliakbar Hedayati Department of Fisheries, Gorgan University of Agricultural Sciences and Natural Resources, Goran, Iran Hamed Ghafari Farsani Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Mohammad Hasan Gerami Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran Journal Article 2014 11 04 This study aimed to evaluate the efficacy of silver sulfate (AgSO4) as a toxicant in goldfish (Carassiusauratus). One hundred and forty-seven live specimens of C. auratus were obtained and exposed to 1, 10, 100, 500, 1000 and 2000 ppm of AgSO4for 96 hours. There was one control group (no AgSO4) and three replicates. The physicochemical properties of water and the following parameters were constant: pH: 7.56±0.45 (TS1); temperature: 19±1°C; hardness: 293±2.35 ppm and dissolved oxygen: 8.80 ±0.06 mg L-1 (DO-5510). LC1, LC10, LC30, LC50, LC70, LC90 and LC99 were calculated in 24, 48, 72 and 96 hours. For assessing the impact ofAgSO4 on physiological responses of goldfish hematological indices, blood glucose and cortisol levels were measured. Results showed that LC50 96-h of AgSO4 for goldfish was 687.81 ppm. In addition, the use of AgSO4induces a significant decrease in MCHE after 48 hours, MCV and MCH after 96 hours and lymphocyte after 96 hours in contrast to the control group (P<0.05). Furthermore, increased lymphocyte was significant after 24 hours exposure (P<0.05). In addition, glucose increased significantly at P<0.05 with time increase24 hours after experiment but this (). In conclusion, the study showed that acute toxicity of AgSO4induced hematological alterations in goldfish and offers a tool for the evaluation oftoxicity-derived alterations. https://jpoll.ut.ac.ir/article_53927_d769a21e8cd11d25122f7de20b691a7c.pdf